Review the Research<\/p>\n
Get summaries of key research on vitamin D and COVID-19<\/h5><\/div><\/div><\/div><\/div><\/div>\nPregnancy and COVID-19: The Possible Contribution of Vitamin D<\/span><\/span><\/h1><\/div>Take Home Message<\/span><\/h2><\/div>This <\/span>study <\/span>demonstrat<\/span>es<\/span> a role of vitamin D in affecting the clinical characteristics of pregnant women during COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Results<\/span><\/h2><\/div><\/div><\/div>\n- 160 women were enrolled: 23 resulted positive for at least one SARS-CoV-2 related test (molecular swab or antibody tests).\u00a0<\/span>\u00a0<\/span><\/li>\n
- Vitamin D-associated polymorphisms were able to affect vitamin D levels in SARS-CoV-2 negative and positive subjects: all the VDR TaqICC genotype patients were negative for SARS-CoV-2.<\/span>\u00a0<\/span><\/li>\n
- In a sub-population (118 patients), vitamin D levels correlated with pregnancy-related factors, such as alpha-fetoprotein levels.\u00a0<\/span>\u00a0<\/span><\/li>\n
- Third-trimester vitamin D levels were lower in preterm births compared to full-term pregnancy: this trend was highlighted for SARS-CoV-2 positive patients.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div>![](\"https:\/\/www.vitamindandme.org\/wp-content\/uploads\/2023\/05\/131-Manca-300x147.jpg\" "\\"Pregnant")
<\/span><\/div><\/div><\/div><\/div><\/div>Who<\/span><\/h2><\/div>160 pregnant women.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Things to Keep in Mind<\/span><\/h2><\/div>\n- There were small numbers of SARS-CoV-2-affected patients and PTBs.<\/span>\u00a0<\/span><\/li>\n
- Additional factors associated with inflammation, coagulation or symptoms were not evaluated.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div>
Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div>In conclusion, this is the first study showing a <\/span>possible role<\/span> of vitamin D concentrations and genetic polymorphisms in affecting COVID-19 clinical features in pregnant women; however, studies in larger and independent cohorts are needed to confirm these data<\/span>.<\/span><\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/span><\/h2><\/div>\n- The purpose was to evaluate the influence of vitamin D in affecting some clinical features in pregnancy between SARS-CoV-2 positive and negative patients.<\/span>\u00a0<\/span><\/li>\n
- Vitamin D pathway related polymorphisms and 25-hydroxyvitamin D levels were quantified in pregnant women followed from the first to the third trimester of pregnancy.\u00a0<\/span>\u00a0<\/span><\/li>\n
- Vitamin D deficiency was considered with values \u2264 30 ng\/mL.\u00a0<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Reference<\/span><\/h2><\/div>Manca<\/span> A, <\/span>Cosma<\/span> S, <\/span>Palermiti<\/span> A, Costanzo M, Antonucci M, De Vivo ED, <\/span>Ianniello<\/span> A, <\/span>Borella<\/span> F, <\/span>Carosso<\/span> AR, <\/span>Corcione<\/span> S, De Rosa FG, Benedetto C, <\/span>D’Avolio<\/span> A, <\/span>Cusato<\/span> J. Pregnancy and COVID-19: The Possible Contribution of Vitamin D. Nutrients. 2022 Aug 10;14(16):3275. <\/span>doi<\/span>: 10.3390\/nu14163275. PMID: 36014781; PMCID: PMC9414046.<\/span><\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div>
Pregnancy and COVID-19: The Possible Contribution of Vitamin D<\/span><\/span><\/h1><\/div>Take Home Message<\/span><\/h2><\/div>This <\/span>study <\/span>demonstrat<\/span>es<\/span> a role of vitamin D in affecting the clinical characteristics of pregnant women during COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Results<\/span><\/h2><\/div><\/div><\/div>\n- 160 women were enrolled: 23 resulted positive for at least one SARS-CoV-2 related test (molecular swab or antibody tests).\u00a0<\/span>\u00a0<\/span><\/li>\n
- Vitamin D-associated polymorphisms were able to affect vitamin D levels in SARS-CoV-2 negative and positive subjects: all the VDR TaqICC genotype patients were negative for SARS-CoV-2.<\/span>\u00a0<\/span><\/li>\n
- In a sub-population (118 patients), vitamin D levels correlated with pregnancy-related factors, such as alpha-fetoprotein levels.\u00a0<\/span>\u00a0<\/span><\/li>\n
- Third-trimester vitamin D levels were lower in preterm births compared to full-term pregnancy: this trend was highlighted for SARS-CoV-2 positive patients.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/span><\/div><\/div><\/div><\/div><\/div>Who<\/span><\/h2><\/div>160 pregnant women.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Things to Keep in Mind<\/span><\/h2><\/div>\n- There were small numbers of SARS-CoV-2-affected patients and PTBs.<\/span>\u00a0<\/span><\/li>\n
- Additional factors associated with inflammation, coagulation or symptoms were not evaluated.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div>
Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div>In conclusion, this is the first study showing a <\/span>possible role<\/span> of vitamin D concentrations and genetic polymorphisms in affecting COVID-19 clinical features in pregnant women; however, studies in larger and independent cohorts are needed to confirm these data<\/span>.<\/span><\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/span><\/h2><\/div>\n- The purpose was to evaluate the influence of vitamin D in affecting some clinical features in pregnancy between SARS-CoV-2 positive and negative patients.<\/span>\u00a0<\/span><\/li>\n
- Vitamin D pathway related polymorphisms and 25-hydroxyvitamin D levels were quantified in pregnant women followed from the first to the third trimester of pregnancy.\u00a0<\/span>\u00a0<\/span><\/li>\n
- Vitamin D deficiency was considered with values \u2264 30 ng\/mL.\u00a0<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Reference<\/span><\/h2><\/div>Manca<\/span> A, <\/span>Cosma<\/span> S, <\/span>Palermiti<\/span> A, Costanzo M, Antonucci M, De Vivo ED, <\/span>Ianniello<\/span> A, <\/span>Borella<\/span> F, <\/span>Carosso<\/span> AR, <\/span>Corcione<\/span> S, De Rosa FG, Benedetto C, <\/span>D’Avolio<\/span> A, <\/span>Cusato<\/span> J. Pregnancy and COVID-19: The Possible Contribution of Vitamin D. Nutrients. 2022 Aug 10;14(16):3275. <\/span>doi<\/span>: 10.3390\/nu14163275. PMID: 36014781; PMCID: PMC9414046.<\/span><\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div>
Take Home Message<\/span><\/h2><\/div>This <\/span>study <\/span>demonstrat<\/span>es<\/span> a role of vitamin D in affecting the clinical characteristics of pregnant women during COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Results<\/span><\/h2><\/div><\/div><\/div>\n- 160 women were enrolled: 23 resulted positive for at least one SARS-CoV-2 related test (molecular swab or antibody tests).\u00a0<\/span>\u00a0<\/span><\/li>\n
- Vitamin D-associated polymorphisms were able to affect vitamin D levels in SARS-CoV-2 negative and positive subjects: all the VDR TaqICC genotype patients were negative for SARS-CoV-2.<\/span>\u00a0<\/span><\/li>\n
- In a sub-population (118 patients), vitamin D levels correlated with pregnancy-related factors, such as alpha-fetoprotein levels.\u00a0<\/span>\u00a0<\/span><\/li>\n
- Third-trimester vitamin D levels were lower in preterm births compared to full-term pregnancy: this trend was highlighted for SARS-CoV-2 positive patients.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/span><\/div><\/div><\/div><\/div><\/div>Who<\/span><\/h2><\/div>160 pregnant women.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Things to Keep in Mind<\/span><\/h2><\/div>\n- There were small numbers of SARS-CoV-2-affected patients and PTBs.<\/span>\u00a0<\/span><\/li>\n
- Additional factors associated with inflammation, coagulation or symptoms were not evaluated.<\/span>\u00a0<\/span><\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div>
Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div>In conclusion, this is the first study showing a <\/span>possible role<\/span> of vitamin D concentrations and genetic polymorphisms in affecting COVID-19 clinical features in pregnant women; however, studies in larger and independent cohorts are needed to confirm these data<\/span>.<\/span><\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/span><\/h2><\/div>\n- The purpose was to evaluate the influence of vitamin D in affecting some clinical features in pregnancy between SARS-CoV-2 positive and negative patients.<\/span>\u00a0<\/span><\/li>\n
- Vitamin D pathway related polymorphisms and 25-hydroxyvitamin D levels were quantified in pregnant women followed from the first to the third trimester of pregnancy.\u00a0<\/span>\u00a0<\/span><\/li>\n
- Vitamin D deficiency was considered with values \u2264 30 ng\/mL.\u00a0<\/span>\u00a0<\/span><\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Reference<\/span><\/h2><\/div>Manca<\/span> A, <\/span>Cosma<\/span> S, <\/span>Palermiti<\/span> A, Costanzo M, Antonucci M, De Vivo ED, <\/span>Ianniello<\/span> A, <\/span>Borella<\/span> F, <\/span>Carosso<\/span> AR, <\/span>Corcione<\/span> S, De Rosa FG, Benedetto C, <\/span>D’Avolio<\/span> A, <\/span>Cusato<\/span> J. Pregnancy and COVID-19: The Possible Contribution of Vitamin D. Nutrients. 2022 Aug 10;14(16):3275. <\/span>doi<\/span>: 10.3390\/nu14163275. PMID: 36014781; PMCID: PMC9414046.<\/span><\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div>
This <\/span>study <\/span>demonstrat<\/span>es<\/span> a role of vitamin D in affecting the clinical characteristics of pregnant women during COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> \u00a0<\/span><\/p>\n<\/div><\/div><\/div> 160 pregnant women.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> In conclusion, this is the first study showing a <\/span>possible role<\/span> of vitamin D concentrations and genetic polymorphisms in affecting COVID-19 clinical features in pregnant women; however, studies in larger and independent cohorts are needed to confirm these data<\/span>.<\/span><\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div> \u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> Manca<\/span> A, <\/span>Cosma<\/span> S, <\/span>Palermiti<\/span> A, Costanzo M, Antonucci M, De Vivo ED, <\/span>Ianniello<\/span> A, <\/span>Borella<\/span> F, <\/span>Carosso<\/span> AR, <\/span>Corcione<\/span> S, De Rosa FG, Benedetto C, <\/span>D’Avolio<\/span> A, <\/span>Cusato<\/span> J. Pregnancy and COVID-19: The Possible Contribution of Vitamin D. Nutrients. 2022 Aug 10;14(16):3275. <\/span>doi<\/span>: 10.3390\/nu14163275. PMID: 36014781; PMCID: PMC9414046.<\/span><\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div>Results<\/span><\/h2><\/div><\/div><\/div>
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<\/span><\/div><\/div><\/div><\/div><\/div>Who<\/span><\/h2><\/div>
Things to Keep in Mind<\/span><\/h2><\/div>
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Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>
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Study Design<\/span><\/h2><\/div>
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Reference<\/span><\/h2><\/div>