Review the Research<\/p>\n
Get summaries of key research on vitamin D and COVID-19<\/h5><\/div><\/div><\/div><\/div><\/div>\nLow vitamin D levels and prognosis in a COVID-19 pediatric population: a systematic review<\/h1><\/div>Take Home Message<\/span><\/h2><\/div>In this systematic review of publications studying vitamin D deficiencies and COVID-19 status in adolescents, vitamin D was deficient in 46% of the patients. Those with low levels of vitamin D were more likely to contract COVID-19 and had a 5.5 increased chance of severe disease. <\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/b>Results<\/span><\/h2><\/div><\/div><\/div>\n- Vitamin D deficiency prevalence among participants in the six studies was 45.91% (95% CI; 25.148-67.450).<\/li>\n
- In infected pediatric patients, low levels of vitamin D increased the risk of severe COVID-19 (Odds ratio: 5.5; 95% CI: 1.560-19.515)<\/li>\n<\/ul>\n<\/div><\/div><\/div>
![](\"https:\/\/www.vitamindandme.org\/wp-content\/uploads\/2022\/03\/Young-Asian-boy-in-home-quarantine-300x206.jpg\" "\\"Young")
<\/span><\/div><\/div><\/div><\/div><\/div>Who<\/span><\/h2><\/div>There were six studies including 271 patients less than or equal to 18 years of age.<\/p>\n<\/div><\/div><\/div><\/div><\/div>
Things to Keep in Mind<\/span><\/h2><\/div>\n- The evidence related to the effect of vitamin D on pediatric COVID is limited.<\/li>\n
- There are more studies on vitamin D supplementation and COVID-19 in adults than children.<\/li>\n
- There may be a difference in the benefit of vitamin D supplementation for those who are deficient versus insufficient.<\/li>\n
- The influence of age, gender, and other confounders on vitamin D deficiency and COVID-19 were unavailable.<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div>The systematic review showed that almost half of the pediatric COVID patients suffer from vitamin D deficiency. It is also clear that the deficiency is associated with greater risk of infection and poor outcome in pediatrics. Vitamin D supplementation needs to be explored as a preventive prophylactic, for the prevention and management of COVID-19 in children and adolescents.<\/p>\n<\/div><\/div><\/div>
“<\/span><\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/span><\/h2><\/div>\n- The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement was used in developing and conducting this systematic review.<\/li>\n
- The inclusion criteria were: (1) studies in English, (2) children less than or equal to 18 years of age, (3) COVID-19 positive or negative participants<\/li>\n
- A systematic search of the literature search was done using PubMed, CINAHL, EMBASE,<\/li>\n
- Cochrane Library and Google Scholar databases were performed with keywords COVID-19, SARS-CoV-2, COVID-2019, 2019-nCOV, 2019 novel coronavirus infection, coronavirus disease-19, coronavirus disease 2019, severe acute respiratory, syndrome coronavirus 2, novel coronavirus, vitamin D, vit D, vitamin D supplementation, children, infant, neonate, young, newborn, baby, babies, pediatric, pediatric and juvenile between December 2019 and June 2021.<\/li>\n
- Data extracted included authors, title, country, population, study period, total cases, vitamin D status, severity of COVID-19, vitamin D supplementation, outcomes of the studies, and general consensus.<\/li>\n
- Meta-analysis was performed for assessing the deficiency of vitamin D in pediatric patients of COVID-19.<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>
Low vitamin D levels and prognosis in a COVID-19 pediatric population: a systematic review<\/h1><\/div>Take Home Message<\/span><\/h2><\/div>In this systematic review of publications studying vitamin D deficiencies and COVID-19 status in adolescents, vitamin D was deficient in 46% of the patients. Those with low levels of vitamin D were more likely to contract COVID-19 and had a 5.5 increased chance of severe disease. <\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/b>Results<\/span><\/h2><\/div><\/div><\/div>\n- Vitamin D deficiency prevalence among participants in the six studies was 45.91% (95% CI; 25.148-67.450).<\/li>\n
- In infected pediatric patients, low levels of vitamin D increased the risk of severe COVID-19 (Odds ratio: 5.5; 95% CI: 1.560-19.515)<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/span><\/div><\/div><\/div><\/div><\/div>
Who<\/span><\/h2><\/div>There were six studies including 271 patients less than or equal to 18 years of age.<\/p>\n<\/div><\/div><\/div><\/div><\/div>
Things to Keep in Mind<\/span><\/h2><\/div>\n- The evidence related to the effect of vitamin D on pediatric COVID is limited.<\/li>\n
- There are more studies on vitamin D supplementation and COVID-19 in adults than children.<\/li>\n
- There may be a difference in the benefit of vitamin D supplementation for those who are deficient versus insufficient.<\/li>\n
- The influence of age, gender, and other confounders on vitamin D deficiency and COVID-19 were unavailable.<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div>The systematic review showed that almost half of the pediatric COVID patients suffer from vitamin D deficiency. It is also clear that the deficiency is associated with greater risk of infection and poor outcome in pediatrics. Vitamin D supplementation needs to be explored as a preventive prophylactic, for the prevention and management of COVID-19 in children and adolescents.<\/p>\n<\/div><\/div><\/div>
“<\/span><\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/span><\/h2><\/div>\n- The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement was used in developing and conducting this systematic review.<\/li>\n
- The inclusion criteria were: (1) studies in English, (2) children less than or equal to 18 years of age, (3) COVID-19 positive or negative participants<\/li>\n
- A systematic search of the literature search was done using PubMed, CINAHL, EMBASE,<\/li>\n
- Cochrane Library and Google Scholar databases were performed with keywords COVID-19, SARS-CoV-2, COVID-2019, 2019-nCOV, 2019 novel coronavirus infection, coronavirus disease-19, coronavirus disease 2019, severe acute respiratory, syndrome coronavirus 2, novel coronavirus, vitamin D, vit D, vitamin D supplementation, children, infant, neonate, young, newborn, baby, babies, pediatric, pediatric and juvenile between December 2019 and June 2021.<\/li>\n
- Data extracted included authors, title, country, population, study period, total cases, vitamin D status, severity of COVID-19, vitamin D supplementation, outcomes of the studies, and general consensus.<\/li>\n
- Meta-analysis was performed for assessing the deficiency of vitamin D in pediatric patients of COVID-19.<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>
Take Home Message<\/span><\/h2><\/div>In this systematic review of publications studying vitamin D deficiencies and COVID-19 status in adolescents, vitamin D was deficient in 46% of the patients. Those with low levels of vitamin D were more likely to contract COVID-19 and had a 5.5 increased chance of severe disease. <\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/b>Results<\/span><\/h2><\/div><\/div><\/div>\n- Vitamin D deficiency prevalence among participants in the six studies was 45.91% (95% CI; 25.148-67.450).<\/li>\n
- In infected pediatric patients, low levels of vitamin D increased the risk of severe COVID-19 (Odds ratio: 5.5; 95% CI: 1.560-19.515)<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/span><\/div><\/div><\/div><\/div><\/div>
Who<\/span><\/h2><\/div>There were six studies including 271 patients less than or equal to 18 years of age.<\/p>\n<\/div><\/div><\/div><\/div><\/div>
Things to Keep in Mind<\/span><\/h2><\/div>\n- The evidence related to the effect of vitamin D on pediatric COVID is limited.<\/li>\n
- There are more studies on vitamin D supplementation and COVID-19 in adults than children.<\/li>\n
- There may be a difference in the benefit of vitamin D supplementation for those who are deficient versus insufficient.<\/li>\n
- The influence of age, gender, and other confounders on vitamin D deficiency and COVID-19 were unavailable.<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div>The systematic review showed that almost half of the pediatric COVID patients suffer from vitamin D deficiency. It is also clear that the deficiency is associated with greater risk of infection and poor outcome in pediatrics. Vitamin D supplementation needs to be explored as a preventive prophylactic, for the prevention and management of COVID-19 in children and adolescents.<\/p>\n<\/div><\/div><\/div>
“<\/span><\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/span><\/h2><\/div>\n- The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement was used in developing and conducting this systematic review.<\/li>\n
- The inclusion criteria were: (1) studies in English, (2) children less than or equal to 18 years of age, (3) COVID-19 positive or negative participants<\/li>\n
- A systematic search of the literature search was done using PubMed, CINAHL, EMBASE,<\/li>\n
- Cochrane Library and Google Scholar databases were performed with keywords COVID-19, SARS-CoV-2, COVID-2019, 2019-nCOV, 2019 novel coronavirus infection, coronavirus disease-19, coronavirus disease 2019, severe acute respiratory, syndrome coronavirus 2, novel coronavirus, vitamin D, vit D, vitamin D supplementation, children, infant, neonate, young, newborn, baby, babies, pediatric, pediatric and juvenile between December 2019 and June 2021.<\/li>\n
- Data extracted included authors, title, country, population, study period, total cases, vitamin D status, severity of COVID-19, vitamin D supplementation, outcomes of the studies, and general consensus.<\/li>\n
- Meta-analysis was performed for assessing the deficiency of vitamin D in pediatric patients of COVID-19.<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>
In this systematic review of publications studying vitamin D deficiencies and COVID-19 status in adolescents, vitamin D was deficient in 46% of the patients. Those with low levels of vitamin D were more likely to contract COVID-19 and had a 5.5 increased chance of severe disease. <\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> There were six studies including 271 patients less than or equal to 18 years of age.<\/p>\n<\/div><\/div><\/div><\/div><\/div> \u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> The systematic review showed that almost half of the pediatric COVID patients suffer from vitamin D deficiency. It is also clear that the deficiency is associated with greater risk of infection and poor outcome in pediatrics. Vitamin D supplementation needs to be explored as a preventive prophylactic, for the prevention and management of COVID-19 in children and adolescents.<\/p>\n<\/div><\/div><\/div> \u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/b>Results<\/span><\/h2><\/div><\/div><\/div>
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<\/span><\/div><\/div><\/div><\/div><\/div>Who<\/span><\/h2><\/div>
Things to Keep in Mind<\/span><\/h2><\/div>
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Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>
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Study Design<\/span><\/h2><\/div>
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