Review the Research<\/p>\n
Get summaries of key research on vitamin D and COVID-19<\/h5><\/div><\/div><\/div><\/div><\/div>\nPossible association of vitamin D status with lung involvement and outcome in patients with COVID19: a retrospective study.<\/h1><\/div>Take Home Message<\/span><\/h2><\/div>A lower vitamin D status was associated with negative clinical outcomes and decreased survival in hospitalized patients in Iran with COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Purpose<\/span><\/h2><\/div>To evaluate the prognostic role of serum vitamin D concentration on the extent of lung involvement and final outcomes in patients with COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/b>Results<\/span><\/h2><\/div><\/div><\/div>\n- Lower concentrations of serum 25(OH)D were significantly associated with a greater extent of lung involvement.<\/li>\n
- Lower concentrations of serum 25(OH)D were significantly associated with poorer outcomes in patients with COVID-19.<\/li>\n
- The odds of death were significantly higher in vitamin D deficient patients (25(OH)D\u2009<\u200925 ng\/mL).<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div>![](\"https:\/\/www.vitamindandme.org\/wp-content\/uploads\/2021\/07\/36crop_iStock-1238310494-300x300.jpg\" "\\"36crop_iStock-1238310494\\"")
<\/span><\/div><\/div><\/div><\/div><\/div>Who<\/span><\/h2><\/div>Seventy-three subjects with a confirmed diagnosis of COVID-19 who were admitted to one hospital in Iran between February 28, 2020 and April 19, 2020. \u00a0Average age 55, (47 males, 26 females).<\/p>\n<\/div><\/div><\/div><\/div><\/div>
Things to Keep in Mind<\/span><\/h2><\/div>\n- This study is assessing vitamin D status, not supplementation, and making associations. It doesn\u2019t consider all other aspects of the patient that could influence outcomes.<\/li>\n
- This was not a randomized control trial so it is a bit of a jump for the authors to conclude that supplementation would improve outcomes, the study only suggests an association of vitamin D status and outcomes.<\/li>\n
- The study sample size was small and included only one study center.<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div>This study provides new evidence for clinicians and health policy makers to consider vitamin D supplementation for the improvement of clinical outcomes of patients with COVID-19. We believe that vitamin D might be able to protect patients against developing a severe form of the disease once infected.<\/p>\n<\/div><\/div><\/div>
“<\/span><\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/span><\/h2><\/div>\n- Patients\u2019 demographic data and past medical history including the presence of hypertension, diabetes, ischemic heart disease, asthma, chronic lung disease, chronic liver disease, chronic kidney disease and conditions which might compromise their immune system were recorded.<\/li>\n
- Symptoms including fever, cough, sore throat, dyspnea, chilling, headache, myalgia and gastrointestinal symptoms were collected from medical documents.<\/li>\n
- Vital signs (pulse rate, blood pressure, respiratory rate, body temperature, and oxygen saturation on room air) were recorded for each patient.<\/li>\n
- Patients\u2019 final disease outcome (death vs discharge) was also collected.<\/li>\n
- Serum calcium, phosphorous, magnesium and 25(OH)D were tested.<\/li>\n
- CT scans of the lung were taken.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div>
Reference<\/span><\/h2><\/div>Abrishami A, Dalili N, Mohammadi Torbati P, Asgari R, Arab-Ahmadi M, Behnam B, Sanei-Taheri M. Possible association of vitamin D status with lung involvement and outcome in patients with COVID-19: a retrospective study. Eur J Nutr. 2020 Oct 30:1\u20139. doi: 10.1007\/s00394-020-02411-0. Epub ahead of print. PMID: 33123774; PMCID: PMC7595877.<\/p>\n<\/div><\/div><\/div>
Possible association of vitamin D status with lung involvement and outcome in patients with COVID19: a retrospective study.<\/h1><\/div>Take Home Message<\/span><\/h2><\/div>A lower vitamin D status was associated with negative clinical outcomes and decreased survival in hospitalized patients in Iran with COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Purpose<\/span><\/h2><\/div>To evaluate the prognostic role of serum vitamin D concentration on the extent of lung involvement and final outcomes in patients with COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/b>Results<\/span><\/h2><\/div><\/div><\/div>\n- Lower concentrations of serum 25(OH)D were significantly associated with a greater extent of lung involvement.<\/li>\n
- Lower concentrations of serum 25(OH)D were significantly associated with poorer outcomes in patients with COVID-19.<\/li>\n
- The odds of death were significantly higher in vitamin D deficient patients (25(OH)D\u2009<\u200925 ng\/mL).<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/span><\/div><\/div><\/div><\/div><\/div>Who<\/span><\/h2><\/div>Seventy-three subjects with a confirmed diagnosis of COVID-19 who were admitted to one hospital in Iran between February 28, 2020 and April 19, 2020. \u00a0Average age 55, (47 males, 26 females).<\/p>\n<\/div><\/div><\/div><\/div><\/div>
Things to Keep in Mind<\/span><\/h2><\/div>\n- This study is assessing vitamin D status, not supplementation, and making associations. It doesn\u2019t consider all other aspects of the patient that could influence outcomes.<\/li>\n
- This was not a randomized control trial so it is a bit of a jump for the authors to conclude that supplementation would improve outcomes, the study only suggests an association of vitamin D status and outcomes.<\/li>\n
- The study sample size was small and included only one study center.<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div>This study provides new evidence for clinicians and health policy makers to consider vitamin D supplementation for the improvement of clinical outcomes of patients with COVID-19. We believe that vitamin D might be able to protect patients against developing a severe form of the disease once infected.<\/p>\n<\/div><\/div><\/div>
“<\/span><\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/span><\/h2><\/div>\n- Patients\u2019 demographic data and past medical history including the presence of hypertension, diabetes, ischemic heart disease, asthma, chronic lung disease, chronic liver disease, chronic kidney disease and conditions which might compromise their immune system were recorded.<\/li>\n
- Symptoms including fever, cough, sore throat, dyspnea, chilling, headache, myalgia and gastrointestinal symptoms were collected from medical documents.<\/li>\n
- Vital signs (pulse rate, blood pressure, respiratory rate, body temperature, and oxygen saturation on room air) were recorded for each patient.<\/li>\n
- Patients\u2019 final disease outcome (death vs discharge) was also collected.<\/li>\n
- Serum calcium, phosphorous, magnesium and 25(OH)D were tested.<\/li>\n
- CT scans of the lung were taken.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div>
Reference<\/span><\/h2><\/div>Abrishami A, Dalili N, Mohammadi Torbati P, Asgari R, Arab-Ahmadi M, Behnam B, Sanei-Taheri M. Possible association of vitamin D status with lung involvement and outcome in patients with COVID-19: a retrospective study. Eur J Nutr. 2020 Oct 30:1\u20139. doi: 10.1007\/s00394-020-02411-0. Epub ahead of print. PMID: 33123774; PMCID: PMC7595877.<\/p>\n<\/div><\/div><\/div>
Take Home Message<\/span><\/h2><\/div>A lower vitamin D status was associated with negative clinical outcomes and decreased survival in hospitalized patients in Iran with COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Purpose<\/span><\/h2><\/div>To evaluate the prognostic role of serum vitamin D concentration on the extent of lung involvement and final outcomes in patients with COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/b>Results<\/span><\/h2><\/div><\/div><\/div>\n- Lower concentrations of serum 25(OH)D were significantly associated with a greater extent of lung involvement.<\/li>\n
- Lower concentrations of serum 25(OH)D were significantly associated with poorer outcomes in patients with COVID-19.<\/li>\n
- The odds of death were significantly higher in vitamin D deficient patients (25(OH)D\u2009<\u200925 ng\/mL).<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/span><\/div><\/div><\/div><\/div><\/div>Who<\/span><\/h2><\/div>Seventy-three subjects with a confirmed diagnosis of COVID-19 who were admitted to one hospital in Iran between February 28, 2020 and April 19, 2020. \u00a0Average age 55, (47 males, 26 females).<\/p>\n<\/div><\/div><\/div><\/div><\/div>
Things to Keep in Mind<\/span><\/h2><\/div>\n- This study is assessing vitamin D status, not supplementation, and making associations. It doesn\u2019t consider all other aspects of the patient that could influence outcomes.<\/li>\n
- This was not a randomized control trial so it is a bit of a jump for the authors to conclude that supplementation would improve outcomes, the study only suggests an association of vitamin D status and outcomes.<\/li>\n
- The study sample size was small and included only one study center.<\/li>\n<\/ul>\n
\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>“<\/span><\/h2><\/div><\/div><\/div>This study provides new evidence for clinicians and health policy makers to consider vitamin D supplementation for the improvement of clinical outcomes of patients with COVID-19. We believe that vitamin D might be able to protect patients against developing a severe form of the disease once infected.<\/p>\n<\/div><\/div><\/div>
“<\/span><\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/span><\/h2><\/div>\n- Patients\u2019 demographic data and past medical history including the presence of hypertension, diabetes, ischemic heart disease, asthma, chronic lung disease, chronic liver disease, chronic kidney disease and conditions which might compromise their immune system were recorded.<\/li>\n
- Symptoms including fever, cough, sore throat, dyspnea, chilling, headache, myalgia and gastrointestinal symptoms were collected from medical documents.<\/li>\n
- Vital signs (pulse rate, blood pressure, respiratory rate, body temperature, and oxygen saturation on room air) were recorded for each patient.<\/li>\n
- Patients\u2019 final disease outcome (death vs discharge) was also collected.<\/li>\n
- Serum calcium, phosphorous, magnesium and 25(OH)D were tested.<\/li>\n
- CT scans of the lung were taken.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div>
Reference<\/span><\/h2><\/div>Abrishami A, Dalili N, Mohammadi Torbati P, Asgari R, Arab-Ahmadi M, Behnam B, Sanei-Taheri M. Possible association of vitamin D status with lung involvement and outcome in patients with COVID-19: a retrospective study. Eur J Nutr. 2020 Oct 30:1\u20139. doi: 10.1007\/s00394-020-02411-0. Epub ahead of print. PMID: 33123774; PMCID: PMC7595877.<\/p>\n<\/div><\/div><\/div>
A lower vitamin D status was associated with negative clinical outcomes and decreased survival in hospitalized patients in Iran with COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> To evaluate the prognostic role of serum vitamin D concentration on the extent of lung involvement and final outcomes in patients with COVID-19.<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> \u00a0<\/span><\/p>\n<\/div><\/div><\/div> Seventy-three subjects with a confirmed diagnosis of COVID-19 who were admitted to one hospital in Iran between February 28, 2020 and April 19, 2020. \u00a0Average age 55, (47 males, 26 females).<\/p>\n<\/div><\/div><\/div><\/div><\/div> \u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> This study provides new evidence for clinicians and health policy makers to consider vitamin D supplementation for the improvement of clinical outcomes of patients with COVID-19. We believe that vitamin D might be able to protect patients against developing a severe form of the disease once infected.<\/p>\n<\/div><\/div><\/div> Abrishami A, Dalili N, Mohammadi Torbati P, Asgari R, Arab-Ahmadi M, Behnam B, Sanei-Taheri M. Possible association of vitamin D status with lung involvement and outcome in patients with COVID-19: a retrospective study. Eur J Nutr. 2020 Oct 30:1\u20139. doi: 10.1007\/s00394-020-02411-0. Epub ahead of print. PMID: 33123774; PMCID: PMC7595877.<\/p>\n<\/div><\/div><\/div>Purpose<\/span><\/h2><\/div>
<\/b>Results<\/span><\/h2><\/div><\/div><\/div>
\n
<\/span><\/div><\/div><\/div><\/div><\/div>Who<\/span><\/h2><\/div>
Things to Keep in Mind<\/span><\/h2><\/div>
\n
Author\u2019s Conclusions<\/span><\/h2><\/div><\/div><\/div>
“<\/span><\/h2><\/div><\/div><\/div>
“<\/span><\/h2><\/div><\/div><\/div><\/div><\/div>
Study Design<\/span><\/h2><\/div>
\n
Reference<\/span><\/h2><\/div>