Review the Research<\/p>\n
Get summaries of key research on vitamin D and COVID-19<\/h5><\/div><\/div><\/div><\/div><\/div>\nVitamin D in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients with non-invasive ventilation support<\/span><\/span><\/h1><\/div>Take Home Message<\/h2><\/div>In this study <\/span><\/span><\/span>involving<\/span><\/span><\/span> 118 patients at the San Paolo Hospital in Miliam Italy, <\/span><\/span><\/span>a <\/span><\/span><\/span>significant<\/span><\/span><\/span> proportion<\/span><\/span><\/span> of COVID-19 patients had <\/span><\/span><\/span>vitamin D deficiency and patients requiring assistance with breathing <\/span><\/span><\/span>wer<\/span><\/span><\/span>e even<\/span> more likely to be deficient.<\/span><\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Who<\/h2><\/div>From<\/span><\/span> April<\/span><\/span> 8<\/span><\/span> to<\/span><\/span> May<\/span><\/span> 25<\/span><\/span> 2020<\/span>, 118 patients (74males, 44<\/span><\/span> females; median age 61.0<\/span><\/span> years, range 24-92<\/span><\/span> years) were enrolled in the study<\/span><\/span> conducted <\/span>at<\/span> <\/span>the Respiratory<\/span><\/span><\/span> Unit, ASST Santi Paolo e Carlo, San Paolo Hospital, Milan, Italy<\/span><\/span>.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Purpose<\/h2><\/div>The study was <\/span><\/span><\/span>deisgined<\/span><\/span><\/span> to evaluate <\/span><\/span><\/span>the concentration of <\/span><\/span>VitD<\/span><\/span> in COVID-19 patients experiencing acute respiratory infections of different levels of severity excluding those who underwent invasive respiratory support.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Results<\/h2><\/div><\/div><\/div>\n- T<\/span>here was <\/span>a<\/span>\u00a0<\/span> negative<\/span>\u00a0<\/span> correlation\u00a0 <\/span>between<\/span>\u00a0 <\/span>VitD<\/span>\u00a0 levels\u00a0<\/span> CRP\u00a0<\/span> (<\/span>a marker of inflammation<\/span>)<\/span>.\u00a0\u00a0<\/span>\u00a0<\/span><\/li>\n
- Vit<\/span>n<\/span>D<\/span>\u00a0 levels<\/span>\u00a0 <\/span>in\u00a0 O<\/span>2\u00a0 support<\/span>\u00a0 <\/span>patients\u00a0 were<\/span>\u00a0 significantly higher than in both CPAP and NIMV patients.\u00a0<\/span>\u00a0<\/span><\/li>\n
- No statistical differences were found for CRP levels among <\/span>the three type<\/span> of oxygen support.\u00a0<\/span>\u00a0<\/span><\/li>\n
- Fewer patients <\/span>with\u00a0<\/span> O<\/span>2 support had <\/span>VitD<\/span>\u00a0 <30 ng\/mL and <20 ng\/mL than CPAP and NIMV patients.\u00a0<\/span>\u00a0<\/span><\/li>\n
- There were no relationships between Vit<\/span> D<\/span> or CRP<\/span> and the three classes of IgM and of IgG SARS-CoV-2 antibodies values.\u00a0<\/span>\u00a0<\/span><\/li>\n<\/ul>\n<\/div><\/div><\/div>
![](\"http:\/\/vitamindandme.org\/wp-content\/uploads\/2021\/05\/13Barassi-iStock-1220273396.jpg\")
<\/span><\/div><\/div><\/div><\/div><\/div>Things to Keep in Mind<\/h2><\/div>The authors conclusions are more like recommendations and theory because the main conclusion is really that low vitamin D deficiency is likely in COVID-19 patients and that patients requiring assistance with breathing are even more likely to be deficient. Since <\/span><\/span>there is no complete view of thei<\/span><\/span>r<\/span><\/span> entire health status and history it is challenging to draw <\/span>definitive<\/span> conclusion specific to Vit D.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Author\u2019s Conclusions<\/h2><\/div><\/div><\/div>”<\/h2><\/div><\/div><\/div>Our study shows that a significant proportion of COVID-19 patients have a <\/span><\/span><\/span>VitD<\/span><\/span><\/span> deficiency and that this condition is more frequent in CPAP and in NIMV patients.<\/span><\/span><\/span> <\/span><\/span><\/p>\n<\/div><\/div><\/div>”<\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/h2><\/div>The<\/span> levels of serum <\/span><\/span>VitD<\/span><\/span> and C-reactive protein (CRP) were analyzed<\/span><\/span>. Of th<\/span>e <\/span>patients<\/span>\u00a0<\/span> with<\/span> ventilation support<\/span>,<\/span> 52 (44.1%) received oxygen via nasal cannula, oxygen mask or an oxygen mask with a reservoir, 48 (40.7%) were on a continuous positive airway pressure device (CPAP) and 18 (15,3%) on non-invasive mechanical ventilation (NIMV).<\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>
Vitamin D in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients with non-invasive ventilation support<\/span><\/span><\/h1><\/div>Take Home Message<\/h2><\/div>In this study <\/span><\/span><\/span>involving<\/span><\/span><\/span> 118 patients at the San Paolo Hospital in Miliam Italy, <\/span><\/span><\/span>a <\/span><\/span><\/span>significant<\/span><\/span><\/span> proportion<\/span><\/span><\/span> of COVID-19 patients had <\/span><\/span><\/span>vitamin D deficiency and patients requiring assistance with breathing <\/span><\/span><\/span>wer<\/span><\/span><\/span>e even<\/span> more likely to be deficient.<\/span><\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Who<\/h2><\/div>From<\/span><\/span> April<\/span><\/span> 8<\/span><\/span> to<\/span><\/span> May<\/span><\/span> 25<\/span><\/span> 2020<\/span>, 118 patients (74males, 44<\/span><\/span> females; median age 61.0<\/span><\/span> years, range 24-92<\/span><\/span> years) were enrolled in the study<\/span><\/span> conducted <\/span>at<\/span> <\/span>the Respiratory<\/span><\/span><\/span> Unit, ASST Santi Paolo e Carlo, San Paolo Hospital, Milan, Italy<\/span><\/span>.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Purpose<\/h2><\/div>The study was <\/span><\/span><\/span>deisgined<\/span><\/span><\/span> to evaluate <\/span><\/span><\/span>the concentration of <\/span><\/span>VitD<\/span><\/span> in COVID-19 patients experiencing acute respiratory infections of different levels of severity excluding those who underwent invasive respiratory support.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Results<\/h2><\/div><\/div><\/div>\n- T<\/span>here was <\/span>a<\/span>\u00a0<\/span> negative<\/span>\u00a0<\/span> correlation\u00a0 <\/span>between<\/span>\u00a0 <\/span>VitD<\/span>\u00a0 levels\u00a0<\/span> CRP\u00a0<\/span> (<\/span>a marker of inflammation<\/span>)<\/span>.\u00a0\u00a0<\/span>\u00a0<\/span><\/li>\n
- Vit<\/span>n<\/span>D<\/span>\u00a0 levels<\/span>\u00a0 <\/span>in\u00a0 O<\/span>2\u00a0 support<\/span>\u00a0 <\/span>patients\u00a0 were<\/span>\u00a0 significantly higher than in both CPAP and NIMV patients.\u00a0<\/span>\u00a0<\/span><\/li>\n
- No statistical differences were found for CRP levels among <\/span>the three type<\/span> of oxygen support.\u00a0<\/span>\u00a0<\/span><\/li>\n
- Fewer patients <\/span>with\u00a0<\/span> O<\/span>2 support had <\/span>VitD<\/span>\u00a0 <30 ng\/mL and <20 ng\/mL than CPAP and NIMV patients.\u00a0<\/span>\u00a0<\/span><\/li>\n
- There were no relationships between Vit<\/span> D<\/span> or CRP<\/span> and the three classes of IgM and of IgG SARS-CoV-2 antibodies values.\u00a0<\/span>\u00a0<\/span><\/li>\n<\/ul>\n<\/div><\/div><\/div><\/span><\/div><\/div><\/div><\/div><\/div>
Things to Keep in Mind<\/h2><\/div>The authors conclusions are more like recommendations and theory because the main conclusion is really that low vitamin D deficiency is likely in COVID-19 patients and that patients requiring assistance with breathing are even more likely to be deficient. Since <\/span><\/span>there is no complete view of thei<\/span><\/span>r<\/span><\/span> entire health status and history it is challenging to draw <\/span>definitive<\/span> conclusion specific to Vit D.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Author\u2019s Conclusions<\/h2><\/div><\/div><\/div>”<\/h2><\/div><\/div><\/div>Our study shows that a significant proportion of COVID-19 patients have a <\/span><\/span><\/span>VitD<\/span><\/span><\/span> deficiency and that this condition is more frequent in CPAP and in NIMV patients.<\/span><\/span><\/span> <\/span><\/span><\/p>\n<\/div><\/div><\/div>”<\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/h2><\/div>The<\/span> levels of serum <\/span><\/span>VitD<\/span><\/span> and C-reactive protein (CRP) were analyzed<\/span><\/span>. Of th<\/span>e <\/span>patients<\/span>\u00a0<\/span> with<\/span> ventilation support<\/span>,<\/span> 52 (44.1%) received oxygen via nasal cannula, oxygen mask or an oxygen mask with a reservoir, 48 (40.7%) were on a continuous positive airway pressure device (CPAP) and 18 (15,3%) on non-invasive mechanical ventilation (NIMV).<\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>
Take Home Message<\/h2><\/div>In this study <\/span><\/span><\/span>involving<\/span><\/span><\/span> 118 patients at the San Paolo Hospital in Miliam Italy, <\/span><\/span><\/span>a <\/span><\/span><\/span>significant<\/span><\/span><\/span> proportion<\/span><\/span><\/span> of COVID-19 patients had <\/span><\/span><\/span>vitamin D deficiency and patients requiring assistance with breathing <\/span><\/span><\/span>wer<\/span><\/span><\/span>e even<\/span> more likely to be deficient.<\/span><\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Who<\/h2><\/div>From<\/span><\/span> April<\/span><\/span> 8<\/span><\/span> to<\/span><\/span> May<\/span><\/span> 25<\/span><\/span> 2020<\/span>, 118 patients (74males, 44<\/span><\/span> females; median age 61.0<\/span><\/span> years, range 24-92<\/span><\/span> years) were enrolled in the study<\/span><\/span> conducted <\/span>at<\/span> <\/span>the Respiratory<\/span><\/span><\/span> Unit, ASST Santi Paolo e Carlo, San Paolo Hospital, Milan, Italy<\/span><\/span>.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Purpose<\/h2><\/div>The study was <\/span><\/span><\/span>deisgined<\/span><\/span><\/span> to evaluate <\/span><\/span><\/span>the concentration of <\/span><\/span>VitD<\/span><\/span> in COVID-19 patients experiencing acute respiratory infections of different levels of severity excluding those who underwent invasive respiratory support.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Results<\/h2><\/div><\/div><\/div>\n- T<\/span>here was <\/span>a<\/span>\u00a0<\/span> negative<\/span>\u00a0<\/span> correlation\u00a0 <\/span>between<\/span>\u00a0 <\/span>VitD<\/span>\u00a0 levels\u00a0<\/span> CRP\u00a0<\/span> (<\/span>a marker of inflammation<\/span>)<\/span>.\u00a0\u00a0<\/span>\u00a0<\/span><\/li>\n
- Vit<\/span>n<\/span>D<\/span>\u00a0 levels<\/span>\u00a0 <\/span>in\u00a0 O<\/span>2\u00a0 support<\/span>\u00a0 <\/span>patients\u00a0 were<\/span>\u00a0 significantly higher than in both CPAP and NIMV patients.\u00a0<\/span>\u00a0<\/span><\/li>\n
- No statistical differences were found for CRP levels among <\/span>the three type<\/span> of oxygen support.\u00a0<\/span>\u00a0<\/span><\/li>\n
- Fewer patients <\/span>with\u00a0<\/span> O<\/span>2 support had <\/span>VitD<\/span>\u00a0 <30 ng\/mL and <20 ng\/mL than CPAP and NIMV patients.\u00a0<\/span>\u00a0<\/span><\/li>\n
- There were no relationships between Vit<\/span> D<\/span> or CRP<\/span> and the three classes of IgM and of IgG SARS-CoV-2 antibodies values.\u00a0<\/span>\u00a0<\/span><\/li>\n<\/ul>\n<\/div><\/div><\/div><\/span><\/div><\/div><\/div><\/div><\/div>
Things to Keep in Mind<\/h2><\/div>The authors conclusions are more like recommendations and theory because the main conclusion is really that low vitamin D deficiency is likely in COVID-19 patients and that patients requiring assistance with breathing are even more likely to be deficient. Since <\/span><\/span>there is no complete view of thei<\/span><\/span>r<\/span><\/span> entire health status and history it is challenging to draw <\/span>definitive<\/span> conclusion specific to Vit D.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Author\u2019s Conclusions<\/h2><\/div><\/div><\/div>”<\/h2><\/div><\/div><\/div>Our study shows that a significant proportion of COVID-19 patients have a <\/span><\/span><\/span>VitD<\/span><\/span><\/span> deficiency and that this condition is more frequent in CPAP and in NIMV patients.<\/span><\/span><\/span> <\/span><\/span><\/p>\n<\/div><\/div><\/div>”<\/h2><\/div><\/div><\/div><\/div><\/div>Study Design<\/h2><\/div>The<\/span> levels of serum <\/span><\/span>VitD<\/span><\/span> and C-reactive protein (CRP) were analyzed<\/span><\/span>. Of th<\/span>e <\/span>patients<\/span>\u00a0<\/span> with<\/span> ventilation support<\/span>,<\/span> 52 (44.1%) received oxygen via nasal cannula, oxygen mask or an oxygen mask with a reservoir, 48 (40.7%) were on a continuous positive airway pressure device (CPAP) and 18 (15,3%) on non-invasive mechanical ventilation (NIMV).<\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>
In this study <\/span><\/span><\/span>involving<\/span><\/span><\/span> 118 patients at the San Paolo Hospital in Miliam Italy, <\/span><\/span><\/span>a <\/span><\/span><\/span>significant<\/span><\/span><\/span> proportion<\/span><\/span><\/span> of COVID-19 patients had <\/span><\/span><\/span>vitamin D deficiency and patients requiring assistance with breathing <\/span><\/span><\/span>wer<\/span><\/span><\/span>e even<\/span> more likely to be deficient.<\/span><\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> From<\/span><\/span> April<\/span><\/span> 8<\/span><\/span> to<\/span><\/span> May<\/span><\/span> 25<\/span><\/span> 2020<\/span>, 118 patients (74males, 44<\/span><\/span> females; median age 61.0<\/span><\/span> years, range 24-92<\/span><\/span> years) were enrolled in the study<\/span><\/span> conducted <\/span>at<\/span> <\/span>the Respiratory<\/span><\/span><\/span> Unit, ASST Santi Paolo e Carlo, San Paolo Hospital, Milan, Italy<\/span><\/span>.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> The study was <\/span><\/span><\/span>deisgined<\/span><\/span><\/span> to evaluate <\/span><\/span><\/span>the concentration of <\/span><\/span>VitD<\/span><\/span> in COVID-19 patients experiencing acute respiratory infections of different levels of severity excluding those who underwent invasive respiratory support.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> The authors conclusions are more like recommendations and theory because the main conclusion is really that low vitamin D deficiency is likely in COVID-19 patients and that patients requiring assistance with breathing are even more likely to be deficient. Since <\/span><\/span>there is no complete view of thei<\/span><\/span>r<\/span><\/span> entire health status and history it is challenging to draw <\/span>definitive<\/span> conclusion specific to Vit D.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div> Our study shows that a significant proportion of COVID-19 patients have a <\/span><\/span><\/span>VitD<\/span><\/span><\/span> deficiency and that this condition is more frequent in CPAP and in NIMV patients.<\/span><\/span><\/span> <\/span><\/span><\/p>\n<\/div><\/div><\/div> The<\/span> levels of serum <\/span><\/span>VitD<\/span><\/span> and C-reactive protein (CRP) were analyzed<\/span><\/span>. Of th<\/span>e <\/span>patients<\/span>\u00a0<\/span> with<\/span> ventilation support<\/span>,<\/span> 52 (44.1%) received oxygen via nasal cannula, oxygen mask or an oxygen mask with a reservoir, 48 (40.7%) were on a continuous positive airway pressure device (CPAP) and 18 (15,3%) on non-invasive mechanical ventilation (NIMV).<\/span>\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div>Who<\/h2><\/div>
Purpose<\/h2><\/div>
Results<\/h2><\/div><\/div><\/div>
\n
<\/span><\/div><\/div><\/div><\/div><\/div>Things to Keep in Mind<\/h2><\/div>
Author\u2019s Conclusions<\/h2><\/div><\/div><\/div>
”<\/h2><\/div><\/div><\/div>
”<\/h2><\/div><\/div><\/div><\/div><\/div>
Study Design<\/h2><\/div>