{"id":1782,"date":"2021-02-18T16:15:25","date_gmt":"2021-02-18T21:15:25","guid":{"rendered":"https:\/\/test-crn-owl-wp.aspirant.com\/?p=1782"},"modified":"2021-02-18T16:15:25","modified_gmt":"2021-02-18T21:15:25","slug":"low-vitamin-d-status-at-admission-as-a-risk-factor-for-poor-survival-in-hospitalized-patients-with-covid-19-an-italian-retrospective-study","status":"publish","type":"post","link":"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2021\/02\/18\/low-vitamin-d-status-at-admission-as-a-risk-factor-for-poor-survival-in-hospitalized-patients-with-covid-19-an-italian-retrospective-study\/","title":{"rendered":"Low Vitamin D Status at Admission as a Risk Factor for Poor Survival in Hospitalized Patients With COVID-19: An Italian Retrospective Study"},"content":{"rendered":"<p><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container custom-title hundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--link_hover_color: #31525b;--awb-border-sizes-top:0;--awb-border-sizes-bottom:0;--awb-border-sizes-left:0;--awb-border-sizes-right:0;--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:0px;--awb-padding-right:0px;--awb-padding-bottom:0px;--awb-padding-left:0px;--awb-margin-top:0px;--awb-margin-bottom:0px;--awb-background-color:#310a31;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"width:104% !important;max-width:104% !important;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_2 1_2 fusion-flex-column custom-title-image\" style=\"--awb-padding-top:0px;--awb-padding-right:0px;--awb-padding-bottom:0px;--awb-padding-left:0px;--awb-bg-image:url(&#039;https:\/\/www.vitamindandme.org\/wp-content\/uploads\/2021\/04\/review-the-research-4.jpg&#039;);--awb-bg-size:cover;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:3.84%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:3.84%;--awb-width-medium:50%;--awb-order-medium:0;--awb-spacing-right-medium:3.84%;--awb-spacing-left-medium:3.84%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column fusion-empty-column-bg-image fusion-column-has-bg-image\" data-bg-url=\"https:\/\/www.vitamindandme.org\/wp-content\/uploads\/2021\/04\/review-the-research-4.jpg\"><img decoding=\"async\" class=\"fusion-empty-dims-img-placeholder fusion-no-large-visibility\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\"><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_2 1_2 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:3.84%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:3.84%;--awb-width-medium:50%;--awb-order-medium:0;--awb-spacing-right-medium:3.84%;--awb-spacing-left-medium:3.84%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#f7f9f9;--awb-margin-top:20%;--awb-font-size:36px;\"><h2 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:42px;\"><p>Review the Research<\/p>\n<div class=\"fusion-text fusion-text-1\"><\/div><\/h2><\/div><div class=\"fusion-title title fusion-title-2 fusion-sep-none fusion-title-text fusion-title-size-five\" style=\"--awb-text-color:#f7f9f9;--awb-margin-bottom:20%;--awb-font-size:16px;\"><h5 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:16px;\">Get summaries of key research on vitamin D and COVID-19<\/h5><\/div><\/div><\/div><\/div><\/div>\n<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-2 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:5%;--awb-background-color:#f7f9f9;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-3 fusion-sep-none fusion-title-text fusion-title-size-one\" style=\"--awb-text-color:#310a31;--awb-margin-bottom:8%;--awb-font-size:36px;\"><h1 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:60px;\"><span class=\"TextRun SCXW20210047 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW20210047 BCX2\">Low Vitamin D Status at Admission as a Risk Factor for Poor Survival in Hospitalized Patients With COVID-19: An Italian Retrospective Study<\/span><\/span><\/h1><\/div><div class=\"fusion-title title fusion-title-4 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#065143;--awb-margin-bottom:3%;--awb-font-size:36px;\"><h2 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:60px;\">Take Home Message<\/h2><\/div><div class=\"fusion-text fusion-text-2\"><p><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">S<\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun CommentStart SCXW224262272 BCX2\">tudy participants<\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\"> were <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">137<\/span><\/span> <span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">patients<\/span><\/span> <span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">who were <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">admitted to <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">a <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">hospital <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">in Rome Italy between March 1 and April 30, <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun ContextualSpellingAndGrammarErrorV2 SCXW224262272 BCX2\">2020<\/span><\/span> <span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">with COVID-19<\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\"> who<\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\"> had serum 25(OH)D levels &lt; 75 nmol\/L<\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">, suggesting a possible role of low vitamin D status in increasing<\/span><\/span> <span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">the risk of SARS-CoV-2 infection and subsequent hospitalization. The association<\/span><\/span> <span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">between <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">low <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">serum 25(OH)D levels and <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">increased <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">risk of in-hospital mortality observed in <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">the study<\/span><\/span> <span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">group<\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\"> suggests<\/span><\/span> <span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">that a lower vitamin D status upon admission may represent a modifiable and independent risk<\/span><\/span> <span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">factor for poor prognosis <\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\">with<\/span><\/span><span class=\"TextRun SCXW224262272 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW224262272 BCX2\"> COVID-19.<\/span><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-3 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:5%;--awb-background-color:#f7f9f9;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-3 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-5 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#065143;--awb-margin-bottom:3%;--awb-font-size:36px;\"><h2 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:60px;\">Who<\/h2><\/div><div class=\"fusion-text fusion-text-3\"><p><span data-contrast=\"auto\">One-hundred thirty-seven<\/span><span data-contrast=\"auto\"> consecutive<\/span><span data-contrast=\"auto\">ly admitted <\/span><span data-contrast=\"auto\">COVID-19 positive <\/span><span data-contrast=\"auto\">patients<\/span><span data-contrast=\"auto\"> with\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><span data-contrast=\"auto\">available data on serum <\/span><span data-contrast=\"auto\">vitamin D [<\/span><span data-contrast=\"auto\">25(OH)D<\/span><span data-contrast=\"auto\">]<\/span><span data-contrast=\"auto\"> levels, who were admitted to <\/span><span data-contrast=\"auto\">Tor Vergata University<\/span> <span data-contrast=\"auto\">Hospital-PTV, Rome, Italy<\/span><span data-contrast=\"auto\"> during the study period.<\/span> <span data-contrast=\"auto\">All patients had laboratory<\/span> <span data-contrast=\"auto\">confirmed<\/span> <span data-contrast=\"auto\">cases of COVID-19, were Caucasian and resided in<\/span> <span data-contrast=\"auto\">the Lazio region<\/span><span data-contrast=\"auto\"> of Italy<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-4 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:5%;--awb-padding-bottom:5%;--awb-background-color:#f7f9f9;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-4 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-6 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#065143;--awb-margin-bottom:3%;--awb-font-size:36px;\"><h2 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:60px;\">Length of Study<\/h2><\/div><div class=\"fusion-text fusion-text-4\"><p><span data-contrast=\"auto\">March 1<\/span><span data-contrast=\"auto\">, 2020<\/span><span data-contrast=\"auto\"> and April 30, 2020<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-5 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:5%;--awb-padding-bottom:5%;--awb-background-color:rgba(0,104,171,0.15);--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-5 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-7 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#065143;--awb-margin-bottom:3%;--awb-font-size:36px;\"><h2 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:60px;\">Results<\/h2><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-6 fusion_builder_column_1_2 1_2 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:3.84%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:3.84%;--awb-width-medium:50%;--awb-order-medium:0;--awb-spacing-right-medium:3.84%;--awb-spacing-left-medium:3.84%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-5\"><ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">Of the 137 COVID-19 patients, 57% s<\/span><span data-contrast=\"auto\">urvi<\/span><span data-contrast=\"auto\">ved<\/span><span data-contrast=\"auto\"> (n<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">78) and <\/span><span data-contrast=\"auto\">43% died (n=59).<\/span><span data-ccp-props=\"{\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">T<\/span><span data-contrast=\"auto\">he survivor group was significantly<\/span><span data-contrast=\"auto\"> younger than <\/span><span data-contrast=\"auto\">the non-survivor group (<\/span><span data-contrast=\"auto\">mean age=<\/span><span data-contrast=\"auto\">65 \u00b1 13<\/span><span data-contrast=\"auto\"> years<\/span><span data-contrast=\"auto\"> vs<\/span> <span data-contrast=\"auto\">70 \u00b1 14 years, respectively).<\/span><span data-ccp-props=\"{\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" aria-setsize=\"-1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">\u00a0The <\/span><span data-contrast=\"auto\">non-<\/span><span data-contrast=\"auto\">survivor group <\/span><span data-contrast=\"auto\">had a significantly higher percentage of men <\/span><span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">78%; n=46<\/span><span data-contrast=\"auto\">)<\/span> <span data-contrast=\"auto\">than the <\/span><span data-contrast=\"auto\">survivor<\/span> <span data-contrast=\"auto\">group (<\/span><span data-contrast=\"auto\">55%; n=43<\/span><span data-contrast=\"auto\">)<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" aria-setsize=\"-1\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"auto\">Median <\/span><span data-contrast=\"auto\">BMI <\/span><span data-contrast=\"auto\">values<\/span> <span data-contrast=\"auto\">between survivors and non-survivors were comparable. However, the percentage of obese patients (defined as<\/span> <span data-contrast=\"auto\">a BMI value of <\/span><span data-contrast=\"auto\">\u00b3<\/span><span data-contrast=\"auto\">30 kg\/m<\/span><span data-contrast=\"auto\">2<\/span><span data-contrast=\"auto\">) was significantly higher in non-survivors<\/span> <span data-contrast=\"auto\">compared to survivors (29% vs 15%; n<\/span><span data-contrast=\"auto\">=<\/span><span data-contrast=\"auto\">17 vs 12<\/span><span data-contrast=\"auto\">).\u00a0<\/span><span data-ccp-props=\"{\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" aria-setsize=\"-1\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"auto\">Among survivors, 35% <\/span><span data-contrast=\"auto\">had<\/span><span data-contrast=\"auto\"> hypertension<\/span> <span data-contrast=\"auto\">and<\/span><span data-contrast=\"auto\">\/or<\/span><span data-contrast=\"auto\"> CVD<\/span> <span data-contrast=\"auto\">(n=27)<\/span><span data-contrast=\"auto\">, <\/span><span data-contrast=\"auto\">10% had <\/span><span data-contrast=\"auto\">diabetes<\/span><span data-contrast=\"auto\"> m<\/span><span data-contrast=\"auto\">ellitus<\/span><span data-contrast=\"auto\"> (n=8)<\/span><span data-contrast=\"auto\"> and 9% <\/span><span data-contrast=\"auto\">had<\/span><span data-contrast=\"auto\"> active or previous malignancy<\/span><span data-contrast=\"auto\"> (n=7)<\/span><span data-contrast=\"auto\">.<\/span> <span data-contrast=\"auto\">Among non-survivors, <\/span><span data-contrast=\"auto\">42% had <\/span><span data-contrast=\"auto\">hypertension and<\/span><span data-contrast=\"auto\">\/or<\/span><span data-contrast=\"auto\"> CVD<\/span><span data-contrast=\"auto\"> (n=25)<\/span><span data-contrast=\"auto\">, 10%<\/span><span data-contrast=\"auto\"> had <\/span><span data-contrast=\"auto\">diabetes mellitus<\/span><span data-contrast=\"auto\"> (n=6) <\/span><span data-contrast=\"auto\">and <\/span><span data-contrast=\"auto\">15% had <\/span><span data-contrast=\"auto\">active or previous malignancy<\/span><span data-contrast=\"auto\"> (n=9)<\/span><span data-contrast=\"auto\">. There<\/span> <span data-contrast=\"auto\">was no statistically significant difference in the percentage of<\/span> <span data-contrast=\"auto\">hypertension and<\/span><span data-contrast=\"auto\">\/or<\/span><span data-contrast=\"auto\"> CVD, diabetes mellitus and active or previous<\/span> <span data-contrast=\"auto\">malignancy between survivors and non-survivors.<\/span><span data-ccp-props=\"{\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" aria-setsize=\"-1\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"auto\">T<\/span><span data-contrast=\"auto\">otal <\/span><span data-contrast=\"auto\">median <\/span><span data-contrast=\"auto\">serum 25(OH)D levels at admission<\/span> <span data-contrast=\"auto\">were significantly higher in survivors than non-survivors<\/span> <span data-contrast=\"auto\">(<\/span><span data-contrast=\"auto\">30<\/span><span data-contrast=\"auto\"> n<\/span><span data-contrast=\"auto\">mol<\/span><span data-contrast=\"auto\">\/L vs <\/span><span data-contrast=\"auto\">20<\/span><span data-contrast=\"auto\"> n<\/span><span data-contrast=\"auto\">mol<\/span><span data-contrast=\"auto\">\/L).\u00a0<\/span><span data-ccp-props=\"{\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" aria-setsize=\"-1\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"auto\">After <\/span><span data-contrast=\"auto\">adjusting for major confounders<\/span> <span data-contrast=\"auto\">(age, sex, obesity, <\/span><span data-contrast=\"auto\">neutrophil-to-lymphocyte count ratio (NLR)<\/span><span data-contrast=\"auto\">, fibrinogen, D-dimer), there<\/span> <span data-contrast=\"auto\">was a significant association between <\/span><span data-contrast=\"auto\">low <\/span><span data-contrast=\"auto\">serum<\/span> <span data-contrast=\"auto\">25(OH)D levels and<\/span><span data-contrast=\"auto\"> greater <\/span><span data-contrast=\"auto\">risk of<\/span> <span data-contrast=\"auto\">COVID-19 in-hospital<\/span> <span data-contrast=\"auto\">mortality<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\">\u00a0<\/span><span data-ccp-props=\"{\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" aria-setsize=\"-1\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"auto\">Non-survivors exhibited significantly higher median levels of<\/span><span data-contrast=\"auto\"> inflammation and immune system activity such as<\/span><span data-contrast=\"auto\"> white blood cell (WBC)<\/span> <span data-contrast=\"auto\">count, NLR, high-sensitivity C-reactive protein (<\/span><span data-contrast=\"auto\">hsCRP<\/span><span data-contrast=\"auto\">), ferritin,<\/span> <span data-contrast=\"auto\">interleukin 6 (IL-6), D-dimer, fibrinogen and procalcitonin (PCT) compared to survivors at<\/span> <span data-contrast=\"auto\">three different time points during hospitalization.<\/span><span data-ccp-props=\"{\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"11\" aria-setsize=\"-1\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"auto\">The best predictive biomarkers for poor prognosis of COVID-19 were <\/span><span data-contrast=\"auto\">hsCRP, NLR, ferritin and D-dimer<\/span><span data-contrast=\"auto\">. <\/span><span data-contrast=\"auto\">IL-6, PCT, fibrinogen,<\/span> <span data-contrast=\"auto\">25(OH)D, WBC count and tumor necrosis factor alpha (TNF-<\/span><span data-contrast=\"auto\">a<\/span><span data-contrast=\"auto\">) may serve as supportive biomarkers<\/span> <span data-contrast=\"auto\">for worse clinical course of the disease.<\/span><span data-ccp-props=\"{\">\u00a0<\/span><\/li>\n<\/ul>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-7 fusion_builder_column_1_2 1_2 fusion-flex-column fusion-flex-align-self-center\" style=\"--awb-bg-size:cover;--awb-width-large:50%;--awb-margin-top-large:0px;--awb-spacing-right-large:3.84%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:3.84%;--awb-width-medium:50%;--awb-order-medium:0;--awb-spacing-right-medium:3.84%;--awb-spacing-left-medium:3.84%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-center fusion-content-layout-column\"><div class=\"fusion-image-element \" style=\"--awb-caption-title-font-family:var(--h2_typography-font-family);--awb-caption-title-font-weight:var(--h2_typography-font-weight);--awb-caption-title-font-style:var(--h2_typography-font-style);--awb-caption-title-size:var(--h2_typography-font-size);--awb-caption-title-transform:var(--h2_typography-text-transform);--awb-caption-title-line-height:var(--h2_typography-line-height);--awb-caption-title-letter-spacing:var(--h2_typography-letter-spacing);\"><span class=\" fusion-imageframe imageframe-none imageframe-1 hover-type-none\"><img decoding=\"async\" width=\"1254\" height=\"836\" src=\"http:\/\/vitamindandme.org\/wp-content\/uploads\/2021\/05\/16Infante-iStock-1254958389.jpg\" alt class=\"img-responsive wp-image-1783\" srcset=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/wp-content\/uploads\/2021\/05\/16Infante-iStock-1254958389-300x200.jpg 300w, http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/wp-content\/uploads\/2021\/05\/16Infante-iStock-1254958389-768x512.jpg 768w, http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/wp-content\/uploads\/2021\/05\/16Infante-iStock-1254958389-1024x683.jpg 1024w, http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/wp-content\/uploads\/2021\/05\/16Infante-iStock-1254958389.jpg 1254w\" sizes=\"(max-width: 1254px) 100vw, 1254px\" \/><\/span><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-6 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:5%;--awb-padding-bottom:5%;--awb-background-color:#f7f9f9;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-8 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-8 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#065143;--awb-margin-bottom:3%;--awb-font-size:36px;\"><h2 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:60px;\">Things to Keep in Mind<\/h2><\/div><div class=\"fusion-text fusion-text-6\"><p><span data-contrast=\"auto\">M<\/span><span data-contrast=\"auto\">ajor limitations of the present<\/span> <span data-contrast=\"auto\">study, includ<\/span><span data-contrast=\"auto\">e:<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"13\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">T<\/span><span data-contrast=\"auto\">he retrospective database design<\/span><span data-contrast=\"auto\">,<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"13\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">S<\/span><span data-contrast=\"auto\">mall sample size,\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"13\" aria-setsize=\"-1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"auto\">L<\/span><span data-contrast=\"auto\">ack of information on chronic lung<\/span> <span data-contrast=\"auto\">disease,\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"13\" aria-setsize=\"-1\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"auto\">L<\/span><span data-contrast=\"auto\">ack of a healthy <\/span><span data-contrast=\"auto\">(non-COVID infected) <\/span><span data-contrast=\"auto\">control group<\/span><span data-contrast=\"auto\">, and<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"13\" aria-setsize=\"-1\" data-aria-posinset=\"5\" data-aria-level=\"1\"><span data-contrast=\"auto\">Its s<\/span><span data-contrast=\"auto\">ingle-center <\/span><span data-contrast=\"auto\">setting<\/span><span data-contrast=\"auto\">, <\/span><span data-contrast=\"auto\">which does not allow<\/span><span data-contrast=\"auto\"> generaliz<\/span><span data-contrast=\"auto\">ation <\/span><span data-contrast=\"auto\">to other <\/span><span data-contrast=\"auto\">populations.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-7 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:5%;--awb-padding-bottom:5%;--awb-background-color:rgba(0,104,171,0.15);--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-9 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-9 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#065143;--awb-margin-bottom:3%;--awb-font-size:36px;\"><h2 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:60px;\">Author\u2019s Conclusions<\/h2><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-10 fusion_builder_column_1_5 1_5 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:20%;--awb-margin-top-large:0px;--awb-spacing-right-large:9.6%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:9.6%;--awb-width-medium:20%;--awb-order-medium:0;--awb-spacing-right-medium:9.6%;--awb-spacing-left-medium:9.6%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-10 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#065143;--awb-margin-bottom:3%;--awb-font-size:48px;\"><h2 class=\"fusion-title-heading title-heading-right\" style=\"margin:0;font-size:1em;line-height:60px;\">&#8221;<\/h2><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-11 fusion_builder_column_3_5 3_5 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:60%;--awb-margin-top-large:0px;--awb-spacing-right-large:3.2%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:3.2%;--awb-width-medium:60%;--awb-order-medium:0;--awb-spacing-right-medium:3.2%;--awb-spacing-left-medium:3.2%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-7\"><p><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">A<\/span><\/span><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\"> high prevalence of hypovitaminosis D <\/span><\/span><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">was found <\/span><\/span><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">in<\/span><\/span> <span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">patients <\/span><\/span><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">hospitalized <\/span><\/span><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">with COVID-19<\/span><\/span><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\"> in Italy<\/span><\/span><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">, suggesting a<\/span><\/span> <span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">possible role of low vitamin D status in increasing the risk<\/span><\/span> <span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">of infection and subsequent hospitalization.<\/span><\/span><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\"> N<\/span><\/span><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">on-survivors exhibited significantly<\/span><\/span> <span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">lower vitamin D levels at admission compared to survivors,<\/span><\/span> <span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">as well as higher levels of markers of inflammation, coagulation<\/span><\/span> <span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">and sepsis. Serum 25(OH)D levels were significantly<\/span><\/span> <span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">inversely associated with the risk of COVID-19<\/span><\/span> <span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">in<\/span><\/span><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">&#8211;<\/span><\/span><span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">hospital<\/span><\/span> <span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">mortality, independent of age, sex, markers of<\/span><\/span> <span class=\"TextRun BCX2 SCXW208383846\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun BCX2 SCXW208383846\">inflammation, coagulation and sepsis, and major comorbidities.<\/span><\/span><\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-12 fusion_builder_column_1_5 1_5 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:20%;--awb-margin-top-large:0px;--awb-spacing-right-large:9.6%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:9.6%;--awb-width-medium:20%;--awb-order-medium:0;--awb-spacing-right-medium:9.6%;--awb-spacing-left-medium:9.6%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-11 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#065143;--awb-margin-bottom:3%;--awb-font-size:48px;\"><h2 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:60px;\">&#8221;<\/h2><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-8 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:5%;--awb-background-color:#f7f9f9;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-13 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-12 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#065143;--awb-margin-bottom:3%;--awb-font-size:36px;\"><h2 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:60px;\">Study Design<\/h2><\/div><div class=\"fusion-text fusion-text-8\"><ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"10\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"auto\">This was a <\/span><span data-contrast=\"auto\">retrospective<\/span><span data-contrast=\"auto\">, single-center<\/span><span data-contrast=\"auto\"> study.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"10\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">All patients received the same standard care for the treatment<\/span> <span data-contrast=\"auto\">of COVID-19 (as per<\/span> <span data-contrast=\"auto\">institutional protocol) consisting<\/span> <span data-contrast=\"auto\">of a combination therapy with dexamethasone plus<\/span> <span data-contrast=\"auto\">hydroxychloroquine and lopinavir\/ritonavir administered<\/span> <span data-contrast=\"auto\">shortly after admission.\u00a0<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"10\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">The 137 p<\/span><span data-contrast=\"auto\">articipants included 89 males (65%) and 48 females (35%).<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"10\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">None of the patients reported<\/span> <span data-contrast=\"auto\">vitamin D supplementation prior to hospital admission.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"10\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">At admission, all 137 patients<\/span> <span data-contrast=\"auto\">showed <\/span><span data-contrast=\"auto\">low vitamin<\/span><span data-contrast=\"auto\"> D<\/span><span data-contrast=\"auto\"> (hypovitaminosis)<\/span><span data-contrast=\"auto\">, defined as serum 25(OH)D levels<\/span> <span data-contrast=\"auto\">&lt;<\/span><span data-contrast=\"auto\">75<\/span><span data-contrast=\"auto\"> n<\/span><span data-contrast=\"auto\">mol<\/span><span data-contrast=\"auto\">\/L according to the Endocrine Society guidelines on<\/span> <span data-contrast=\"auto\">evaluation, treatment and prevention of vitamin D deficiency<\/span><span data-contrast=\"auto\">.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"10\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"auto\">The primary<\/span><span data-contrast=\"auto\"> outcome<\/span><span data-contrast=\"auto\">s measured were<\/span><span data-contrast=\"auto\"> survival <\/span><span data-contrast=\"auto\">and<\/span><span data-contrast=\"auto\"> death<\/span><span data-contrast=\"auto\">.<\/span><span data-contrast=\"auto\"> Data regarding hospital length of stay and intensive care unit length of stay were also collected.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true}\">\u00a0<\/span><\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-9 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:5%;--awb-padding-bottom:5%;--awb-background-color:#f7f9f9;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-14 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-13 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#065143;--awb-margin-bottom:3%;--awb-font-size:36px;\"><h2 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:60px;\">Reference<\/h2><\/div><div class=\"fusion-text fusion-text-9\"><p><span class=\"TextRun SCXW249218484 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"none\"><span class=\"NormalTextRun SCXW249218484 BCX2\">Infante M, <\/span><span class=\"NormalTextRun SpellingErrorV2 SCXW249218484 BCX2\">Buoso<\/span><span class=\"NormalTextRun SCXW249218484 BCX2\"> A, Pieri M, <\/span><span class=\"NormalTextRun SpellingErrorV2 SCXW249218484 BCX2\">Lupisella<\/span><span class=\"NormalTextRun SCXW249218484 BCX2\"> S, <\/span><span class=\"NormalTextRun SpellingErrorV2 SCXW249218484 BCX2\">Nuccetelli<\/span><span class=\"NormalTextRun SCXW249218484 BCX2\"> M, Bernardini S, Fabbri A, Iannetta M, Andreoni M, Colizzi V, Morello M. Low Vitamin D Status at Admission as a Risk Factor for Poor Survival in Hospitalized Patients With COVID-19: An Italian Retrospective Study. J Am Coll <\/span><span class=\"NormalTextRun SpellingErrorV2 SCXW249218484 BCX2\">Nutr<\/span><span class=\"NormalTextRun SCXW249218484 BCX2\">. 2021 Feb 18:1-16. <\/span><span class=\"NormalTextRun SpellingErrorV2 SCXW249218484 BCX2\">doi<\/span><span class=\"NormalTextRun SCXW249218484 BCX2\">: 10.1080\/07315724.2021.1877580. <\/span><span class=\"NormalTextRun SpellingErrorV2 SCXW249218484 BCX2\">Epub<\/span><span class=\"NormalTextRun SCXW249218484 BCX2\"> ahead of print. PMID: 33600292; PMCID: PMC7899172.<\/span><\/span><span class=\"TextRun SCXW249218484 BCX2\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW249218484 BCX2\"> https:\/\/pubmed.ncbi.nlm.nih.gov\/33600292\/<\/span><\/span><\/p>\n<\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-15 fusion_builder_column_1_4 1_4 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:25%;--awb-margin-top-large:0px;--awb-spacing-right-large:7.68%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:7.68%;--awb-width-medium:25%;--awb-order-medium:0;--awb-spacing-right-medium:7.68%;--awb-spacing-left-medium:7.68%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div ><a class=\"fusion-button button-flat fusion-button-default-size button-default fusion-button-default button-1 fusion-button-default-span fusion-button-default-type\" style=\"--button-border-radius-top-left:0;--button-border-radius-top-right:0;--button-border-radius-bottom-right:0;--button-border-radius-bottom-left:0;\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33600292\/\"><span class=\"fusion-button-text\">View Full Abstract<\/span><\/a><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-10 fusion-flex-container research-section nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-background-color:#f7f9f9;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-justify-content-space-between fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-16 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:5%;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:5%;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-title title fusion-title-14 fusion-sep-none fusion-title-text fusion-title-size-two\" style=\"--awb-text-color:#310a31;--awb-margin-bottom:5%;--awb-font-size:36px;\"><h2 class=\"fusion-title-heading title-heading-left\" style=\"margin:0;font-size:1em;line-height:60px;\">Research Summaries<\/h2><\/div><div class=\"fusion-blog-shortcode fusion-blog-shortcode-1 fusion-blog-archive fusion-blog-layout-grid-wrapper fusion-blog-no the-research\"><style type=\"text\/css\">.fusion-blog-shortcode-1 .fusion-blog-layout-grid .fusion-post-grid{padding:30px;}.fusion-blog-shortcode-1 .fusion-posts-container{margin-left: -30px !important; margin-right:-30px !important;}<\/style><div class=\"fusion-posts-container fusion-posts-container-no fusion-no-meta-info fusion-blog-rollover fusion-blog-layout-grid fusion-blog-layout-grid-3 isotope fusion-blog-equal-heights\" data-pages=\"47\" data-grid-col-space=\"60\" style=\"margin: -30px -30px 0;min-height:500px;\"><article id=\"blog-1-post-3396\" class=\"fusion-post-grid post-3396 post type-post status-publish format-standard has-post-thumbnail hentry category-intervention category-meta-analysis category-research\">\n<div class=\"fusion-post-wrapper\" style=\"background-color:rgba(255,255,255,1);border:1px solid #f2f3f5;border-bottom-width:3px;\">\n\n\t\t\t<div class=\"fusion-flexslider flexslider fusion-flexslider-loading fusion-post-slideshow\" style=\"border-color:#f2f3f5;\">\n\t\t<ul class=\"slides\">\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li><div  class=\"fusion-image-wrapper\" aria-haspopup=\"true\">\n\t\t\t\t<img decoding=\"async\" width=\"1356\" height=\"897\" src=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/wp-content\/uploads\/2023\/06\/23-15-Zhang.png\" class=\"attachment-full size-full wp-post-image\" alt=\"\" \/><div class=\"fusion-rollover\">\n\t<div class=\"fusion-rollover-content\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"fusion-rollover-link\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/effect-of-vitamin-d-supplementation-on-covid-19-patients-a-systematic-review-and-meta-analysis\/\">Effect of Vitamin D Supplementation on COVID-19 Patients: A Systematic Review and Meta-Analysis<\/a>\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"fusion-rollover-sep\"><\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"fusion-rollover-gallery\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/wp-content\/uploads\/2023\/06\/23-15-Zhang.png\" data-id=\"3396\" data-rel=\"iLightbox[gallery]\" data-title=\"23-15 Zhang\" data-caption=\"\">\n\t\t\t\t\t\tGallery\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"fusion-rollover-title\">\n\t\t\t\t\t<a class=\"fusion-rollover-title-link\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/effect-of-vitamin-d-supplementation-on-covid-19-patients-a-systematic-review-and-meta-analysis\/\">\n\t\t\t\t\t\tEffect of Vitamin D Supplementation on COVID-19 Patients: A Systematic Review and Meta-Analysis\t\t\t\t\t<\/a>\n\t\t\t\t<\/h4>\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t<div class=\"fusion-rollover-categories\"><a href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/category\/research\/intervention\/\" rel=\"tag\">Intervention<\/a>, <a href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/category\/research\/meta-analysis\/\" rel=\"tag\">Meta Analysis<\/a>, <a href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/category\/research\/\" rel=\"tag\">Research<\/a><\/div>\t\t\t\t\t\n\t\t\n\t\t\t\t\t\t<a class=\"fusion-link-wrapper\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/effect-of-vitamin-d-supplementation-on-covid-19-patients-a-systematic-review-and-meta-analysis\/\" aria-label=\"Effect of Vitamin D Supplementation on COVID-19 Patients: A Systematic Review and Meta-Analysis\"><\/a>\n\t<\/div>\n<\/div>\n<\/div>\n<\/li>\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\n\t<\/div>\n\t<div class=\"fusion-post-content-wrapper\" style=\"padding:30px 25px 25px 25px;\"><div class=\"fusion-post-content post-content\"><h2 class=\"blog-shortcode-post-title entry-title\"><a href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/effect-of-vitamin-d-supplementation-on-covid-19-patients-a-systematic-review-and-meta-analysis\/\">Effect of Vitamin D Supplementation on COVID-19 Patients: A Systematic Review and Meta-Analysis<\/a><\/h2><div class=\"fusion-post-content-container\"><p>  Effect of Vitamin D Supplementation on COVID-19 Patients: A Systematic Review and Meta-Analysis  Take Home Message  This meta-analysis found that vitamin D supplementation significantly reduced mortality from COVID-19 in the cohort<\/p><\/div><\/div><\/div><div class=\"fusion-clearfix\"><\/div><\/div>\n<\/article>\n<article id=\"blog-1-post-3393\" class=\"fusion-post-grid post-3393 post type-post status-publish format-standard has-post-thumbnail hentry category-observational category-research\">\n<div class=\"fusion-post-wrapper\" style=\"background-color:rgba(255,255,255,1);border:1px solid #f2f3f5;border-bottom-width:3px;\">\n\n\t\t\t<div class=\"fusion-flexslider flexslider fusion-flexslider-loading fusion-post-slideshow\" style=\"border-color:#f2f3f5;\">\n\t\t<ul class=\"slides\">\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li><div  class=\"fusion-image-wrapper\" aria-haspopup=\"true\">\n\t\t\t\t<img decoding=\"async\" width=\"1355\" height=\"863\" src=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/wp-content\/uploads\/2023\/06\/23-14-Huang.png\" class=\"attachment-full size-full wp-post-image\" alt=\"\" \/><div class=\"fusion-rollover\">\n\t<div class=\"fusion-rollover-content\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"fusion-rollover-link\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/effect-of-vitamin-d-status-on-adult-covid-19-pneumonia-induced-by-delta-variant-a-longitudinal-real-world-cohort-study\/\">Effect of Vitamin D Status on Adult COVID-19 Pneumonia Induced by Delta Variant: A Longitudinal, Real-World Cohort Study<\/a>\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"fusion-rollover-sep\"><\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"fusion-rollover-gallery\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/wp-content\/uploads\/2023\/06\/23-14-Huang.png\" data-id=\"3393\" data-rel=\"iLightbox[gallery]\" data-title=\"23-14 Huang\" data-caption=\"\">\n\t\t\t\t\t\tGallery\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"fusion-rollover-title\">\n\t\t\t\t\t<a class=\"fusion-rollover-title-link\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/effect-of-vitamin-d-status-on-adult-covid-19-pneumonia-induced-by-delta-variant-a-longitudinal-real-world-cohort-study\/\">\n\t\t\t\t\t\tEffect of Vitamin D Status on Adult COVID-19 Pneumonia Induced by Delta Variant: A Longitudinal, Real-World Cohort Study\t\t\t\t\t<\/a>\n\t\t\t\t<\/h4>\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t<div class=\"fusion-rollover-categories\"><a href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/category\/research\/observational\/\" rel=\"tag\">Observational<\/a>, <a href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/category\/research\/\" rel=\"tag\">Research<\/a><\/div>\t\t\t\t\t\n\t\t\n\t\t\t\t\t\t<a class=\"fusion-link-wrapper\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/effect-of-vitamin-d-status-on-adult-covid-19-pneumonia-induced-by-delta-variant-a-longitudinal-real-world-cohort-study\/\" aria-label=\"Effect of Vitamin D Status on Adult COVID-19 Pneumonia Induced by Delta Variant: A Longitudinal, Real-World Cohort Study\"><\/a>\n\t<\/div>\n<\/div>\n<\/div>\n<\/li>\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\n\t<\/div>\n\t<div class=\"fusion-post-content-wrapper\" style=\"padding:30px 25px 25px 25px;\"><div class=\"fusion-post-content post-content\"><h2 class=\"blog-shortcode-post-title entry-title\"><a href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/effect-of-vitamin-d-status-on-adult-covid-19-pneumonia-induced-by-delta-variant-a-longitudinal-real-world-cohort-study\/\">Effect of Vitamin D Status on Adult COVID-19 Pneumonia Induced by Delta Variant: A Longitudinal, Real-World Cohort Study<\/a><\/h2><div class=\"fusion-post-content-container\"><p>  Effect of Vitamin D Status on Adult COVID-19 Pneumonia Induced by Delta Variant: A Longitudinal, Real-World Cohort Study  Take Home Message  In this small observational study from China in adults with<\/p><\/div><\/div><\/div><div class=\"fusion-clearfix\"><\/div><\/div>\n<\/article>\n<article id=\"blog-1-post-3390\" class=\"fusion-post-grid post-3390 post type-post status-publish format-standard has-post-thumbnail hentry category-meta-analysis category-research\">\n<div class=\"fusion-post-wrapper\" style=\"background-color:rgba(255,255,255,1);border:1px solid #f2f3f5;border-bottom-width:3px;\">\n\n\t\t\t<div class=\"fusion-flexslider flexslider fusion-flexslider-loading fusion-post-slideshow\" style=\"border-color:#f2f3f5;\">\n\t\t<ul class=\"slides\">\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li><div  class=\"fusion-image-wrapper\" aria-haspopup=\"true\">\n\t\t\t\t<img decoding=\"async\" width=\"1606\" height=\"896\" src=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/wp-content\/uploads\/2023\/06\/23-13-Bignardi.png\" class=\"attachment-full size-full wp-post-image\" alt=\"\" \/><div class=\"fusion-rollover\">\n\t<div class=\"fusion-rollover-content\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"fusion-rollover-link\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/is-the-vitamin-d-status-of-patients-with-covid-19-associated-with-reduced-mortality-a-systematic-review-and-meta-analysis\/\">Is the Vitamin D Status of Patients with COVID-19 Associated with Reduced Mortality? A Systematic Review and Meta-Analysis<\/a>\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"fusion-rollover-sep\"><\/div>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"fusion-rollover-gallery\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/wp-content\/uploads\/2023\/06\/23-13-Bignardi.png\" data-id=\"3390\" data-rel=\"iLightbox[gallery]\" data-title=\"23-13 Bignardi\" data-caption=\"\">\n\t\t\t\t\t\tGallery\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"fusion-rollover-title\">\n\t\t\t\t\t<a class=\"fusion-rollover-title-link\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/is-the-vitamin-d-status-of-patients-with-covid-19-associated-with-reduced-mortality-a-systematic-review-and-meta-analysis\/\">\n\t\t\t\t\t\tIs the Vitamin D Status of Patients with COVID-19 Associated with Reduced Mortality? A Systematic Review and Meta-Analysis\t\t\t\t\t<\/a>\n\t\t\t\t<\/h4>\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t<div class=\"fusion-rollover-categories\"><a href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/category\/research\/meta-analysis\/\" rel=\"tag\">Meta Analysis<\/a>, <a href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/category\/research\/\" rel=\"tag\">Research<\/a><\/div>\t\t\t\t\t\n\t\t\n\t\t\t\t\t\t<a class=\"fusion-link-wrapper\" href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/is-the-vitamin-d-status-of-patients-with-covid-19-associated-with-reduced-mortality-a-systematic-review-and-meta-analysis\/\" aria-label=\"Is the Vitamin D Status of Patients with COVID-19 Associated with Reduced Mortality? A Systematic Review and Meta-Analysis\"><\/a>\n\t<\/div>\n<\/div>\n<\/div>\n<\/li>\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\n\t<\/div>\n\t<div class=\"fusion-post-content-wrapper\" style=\"padding:30px 25px 25px 25px;\"><div class=\"fusion-post-content post-content\"><h2 class=\"blog-shortcode-post-title entry-title\"><a href=\"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/2023\/06\/01\/is-the-vitamin-d-status-of-patients-with-covid-19-associated-with-reduced-mortality-a-systematic-review-and-meta-analysis\/\">Is the Vitamin D Status of Patients with COVID-19 Associated with Reduced Mortality? A Systematic Review and Meta-Analysis<\/a><\/h2><div class=\"fusion-post-content-container\"><p>  Is the Vitamin D Status of Patients with COVID-19 Associated with Reduced Mortality? A Systematic Review and Meta-Analysis  Take Home Message  his meta-analysis found that overall vitamin D deficiency was associated<\/p><\/div><\/div><\/div><div class=\"fusion-clearfix\"><\/div><\/div>\n<\/article>\n<div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-17 fusion_builder_column_1_1 1_1 fusion-flex-column news-section\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:1.92%;--awb-margin-bottom-large:20px;--awb-spacing-left-large:1.92%;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:1.92%;--awb-spacing-left-medium:1.92%;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-10 more-news\" style=\"--awb-content-alignment:right;--awb-font-size:18px;\"><p><a href=\"\/research\">View All <i class=\"fas fa-arrow-right\"><\/i><\/a><\/p>\n<\/div><\/div><\/div><\/div><\/div><div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-11 fusion-flex-container has-pattern-background has-mask-background disclaimer-section nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-padding-top:7%;--awb-padding-bottom:2%;--awb-background-color:rgba(0,104,171,0.15);--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1248px;margin-left: calc(-4% \/ 2 );margin-right: calc(-4% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-18 fusion_builder_column_1_1 1_1 fusion-flex-column disclaimer-wrapper\" style=\"--awb-padding-top:0px;--awb-padding-right:45px;--awb-padding-bottom:0px;--awb-padding-left:45px;--awb-bg-color:#f7f9f9;--awb-bg-color-hover:#f7f9f9;--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:0;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:0;--awb-spacing-left-medium:0;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:1.92%;--awb-spacing-left-small:1.92%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-content-boxes content-boxes columns row fusion-columns-1 fusion-columns-total-1 fusion-content-boxes-1 content-boxes-icon-on-side content-left\" style=\"--awb-margin-top:2%;--awb-margin-bottom:0px;--awb-hover-accent-color:#065143;--awb-circle-hover-accent-color:transparent;--awb-item-margin-bottom:40px;\" data-animationOffset=\"top-into-view\"><div style=\"--awb-backgroundcolor:rgba(255,255,255,0);\" class=\"fusion-column content-box-column content-box-column content-box-column-1 col-lg-12 col-md-12 col-sm-12 fusion-content-box-hover content-box-column-last content-box-column-last-in-row\"><div class=\"col content-box-wrapper content-wrapper link-area-link-icon content-icon-wrapper-yes icon-hover-animation-none\" data-animationOffset=\"top-into-view\"><div class=\"heading icon-left\"><h2 class=\"content-box-heading\" style=\"--h2_typography-font-size:24px;line-height:29px;\">Disclaimer<\/h2><\/div><div class=\"fusion-clearfix\"><\/div><div class=\"content-container\">Information on this website should not be considered medical advice for COVID-19 or any other illness.\u202f If you are concerned that you may have COVID-19 or other serious illness, you should contact your healthcare practitioner immediately.\u202f Always talk to your healthcare practitioner about any dietary supplements you are taking or plan to take.\u202f <a href=\"http:\/\/disclaimer\/\">Click here<\/a> to learn more about the content on this website.\u00a0<\/div><\/div><\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><\/div><\/div>\n<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Study participants were 137 patients who were admitted to a hospital in Rome Italy between March 1 and April 30, 2020 with COVID-19 who had serum 25(OH)D levels < 75 nmol\/L, suggesting a possible role of low vitamin D status in increasing the risk of SARS-CoV-2 infection and subsequent hospitalization. The association between low serum 25(OH)D levels and increased risk of in-hospital mortality observed in the study group suggests that a lower vitamin D status upon admission may represent a modifiable and independent risk factor for poor prognosis with COVID-19.\n<\/p>\n","protected":false},"author":1,"featured_media":1840,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[12,6],"tags":[],"class_list":["post-1782","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-observational","category-research"],"_links":{"self":[{"href":"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/1782","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/comments?post=1782"}],"version-history":[{"count":0,"href":"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/posts\/1782\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/media\/1840"}],"wp:attachment":[{"href":"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/media?parent=1782"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/categories?post=1782"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/a-ac-dev-app-crn-vdm-wp.azurewebsites.net\/index.php\/wp-json\/wp\/v2\/tags?post=1782"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}